Frequently Asked Questions
How do GLP-1 medications cause weight loss?
They mimic gut hormones that slow gastric emptying, increase satiety signals in the brain, and reduce appetite. You feel fuller sooner and stay full longer, naturally eating less. Tirzepatide adds GIP receptor action, which appears to amplify these effects.
What happens to weight after stopping the medication?
Most of the lost weight returns. The STEP-4 trial documented roughly two-thirds regain within 12 months of stopping semaglutide. This is why clinicians treat these medications as chronic therapy similar to blood pressure or cholesterol medication.
Is this projection a guarantee?
No. The calculator applies trial-average data to estimate a range. Some people lose significantly more, others significantly less. Slow responders, those with lower adherence, or those who stop early will see results below the average. Use the projection as a planning tool, not a promise.
Why does the calculator cap adherence at 30%?
Below roughly 30% of prescribed doses, the pharmacological effect is minimal and any remaining loss is primarily attributable to behavioral change rather than the drug. The 30% floor prevents the model from producing misleading near-zero projections that could be misread as zero drug effect.
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General information only. Not medical advice.
Health & Medical Disclaimer: General information only. Not medical advice.
This calculator provides general health information only and is not medical advice. Results do not replace professional medical evaluation or diagnosis. Consult a licensed healthcare provider before making health decisions. Always seek immediate medical attention for emergencies.